Exploring Seipin: From Biochemistry to Bioinformatics Predictions
نویسندگان
چکیده
منابع مشابه
Seipin: from human disease to molecular mechanism.
The most-severe form of congenital generalized lipodystrophy (CGL) is caused by mutations in BSCL2/seipin. Seipin is a homo-oligomeric integral membrane protein in the endoplasmic reticulum that concentrates at junctions with cytoplasmic lipid droplets (LDs). While null mutations in seipin are responsible for lipodystrophy, dominant mutations cause peripheral neuropathy and other nervous system...
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ژورنال
عنوان ژورنال: International Journal of Cell Biology
سال: 2018
ISSN: 1687-8876,1687-8884
DOI: 10.1155/2018/5207608